This is a post I wrote on company's internal wiki... just want a backup here.
Three points to bear in mind:
 Outliers are not bad; they just behave differently.
 Many statistics are sensitive to outliers. e.g. the mean and every model that relies on the mean.
 Abnormal detection is another topic; this post focus on exploring robust models.
Make the analysis robust to outliers:
Method

Action

Advantage

Concern


Remove the outliers  remove outliers according to a certain threshold or calculation (perhaps via unsupervised models); only focus on the left subsample.  In most cases the signal will be more clear from concentrated subsample.  Hard to generalize the effect to entire population; hard to define a threshold. 
Capping the outliers  cap the outliers to a certain value.  All observations are kept so easy to map the effect to all samples afterward; outliers' impacts are punished.  softer compared to removing the outliers; hard to find the threshold or capping rule. 
Control for covariates  include some control variables in the regression. some how analyze the "difference" but not just linear and constant difference.  Introduce some relevant factors to gain a precise estimation and better learning.  Need to find the right control variable. Irrelevant covariates will only introduce noise. 
Regression to the median  Median is more robust than the mean when outliers persist. Run a full quantile regression if possible; or just 50% quantile which is the median regression.  Get a clear directional signal; robust to outliers so no need to choose any threshold.  Hard to generalize the treatment effect to all population. 
Quantile Regression  Generalized model from above; help you understand subtle difference in each quantile.  Gain more knowledge on the distribution rather than single point and great explanation power.  Computational expensive; hard for further generalization; 
Subsample Regression  Instead of regress to each quantile, a subsample regression only run regression within each strata of the whole sample (say, subregression in each decile).  Identical to introducing a categorical variable for each decile in regression; also help inspect each subsample.  only directional; higher accumulated falsepositive rate. 
Take log() or other numerical transformations  It's a numerical trick that shrink the range to a narrower one (high punishment on the high values).  Easy to compute and map back to the real value; get directional results.  May not be enough to obtain a clear signal. 
Unsupervised study for higher dimensions  This is more about outlier detection. When there are more than one dimension to define an outlier, some unsupervised models like Kmeans would help (identify the distance to the center).  deals with higher dimensions  exploration only.

Rank based methods  Measure ranks of outcome variables instead of the absolute value.  immunized to outliers.  Hard to generalize the treatment effect to all population.

That's all I could think of for now...any addition is welcome ðŸ™‚
 update on Apr 8, 2016 
Some new notes:
 "outliers" may not be the right name for heavy tails.
 Rank methods.